| Nov 7 | Non-Conf | vs. Anderson University (SC) | 51–0 | 1-0 | — |
| Nov 7 | Non-Conf | vs. CSU Bakersfield | 19–15 | 2-0 | — |
| Nov 7 | Conf | vs. Davidson | 49–0 | 3-0 | — |
| Nov 8 | Tourn | Hokie Open | — | — | Rector Field House · Blacksburg, VA |
| Nov 8 | Tourn | Hokie Open (Fresh/Soph) | — | — | Rector Field House · Blacksburg, VA |
| Nov 15 | Tourn | Michigan State Open | — | — | Jenison Fieldhouse · East Lansing, MI |
| Nov 15 | Tourn | Michigan State Open (Fresh/Soph) | — | — | Jenison Fieldhouse · East Lansing, MI |
| Nov 22 | Tourn | Keystone Classic | — | — | University Of Pennsylvania · Philadelphia, PA |
| Nov 29 | Non-Conf | vs. North Carolina | 12–24 | 3-1 | — |
| Dec 4 | Non-Conf | vs. North Carolina State | 14–21 | 3-2 | — |
| Dec 15 | Non-Conf | vs. Duke | 26–14 | 4-2 | — |
| Dec 19 | Non-Conf | vs. Clarion | 30–6 | 5-2 | — |
| Dec 19 | Non-Conf | vs. Buffalo | 19–12 | 6-2 | — |
| Jan 3 | Tourn | Southern Scuffle | — | — | McKenzie Arena · Chattanooga, TN |
| Jan 6 | Conf | vs. Campbell | 28–12 | 7-2 | — |
| Jan 10 | Non-Conf | vs. SIUE | 33–8 | 8-2 | — |
| Jan 20 | Conf | vs. Citadel | 31–13 | 9-2 | — |
| Jan 26 | Conf | vs. Gardner-Webb | 18–22 | 9-3 | — |
| Feb 5 | Conf | @ Chattanooga | 22–15 | 10-3 | — |
| Feb 11 | Conf | vs. Virginia Military Institute | 27–9 | 11-3 | — |
| Feb 12 | Non-Conf | vs. Missouri | 6–41 | 11-4 | — |
| Feb 21 | Non-Conf | vs. Indiana | 21–13 | 12-4 | — |
| Mar 5 | SoCon Champs | Southern Conference Championships | 83.51st | — | Kimmel Arena · Asheville, NC |
| Mar 17 | NCAA Champs | 2016 NCAA Championships | — | — | Madison Square Garden · New York, NY |
